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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074e500ea6fa7108301ebd8eb78ed914aeaa28a0a1900be3a2277b02fd6e4b1c' 
  AND token = '423g9sTWHt0gfau7xD0xLEWzkCsXtND+ggBbD8XQcyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}