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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9259d16d65ae7ea89b4b6683dd4fca67e8b099dc63a1b0570c7a481711bf0dce' 
  AND token = '4IHx+tHXu+CxTXQxu6zJ/OO+5Jc+Em7yM9+8eO6vkWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}