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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec6f201f641d07f4bd38447834249dfee78f4b5c6943f54c54c4e3bf11a54ee' 
  AND token = '/txHxiAUPS+wJNyxKL6QSry8/WqW+MRvLuu6vSFcT4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}