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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2633ac50bd2294969115d93ae9df3745ee30af44476257185453ae38cac59f7e' 
  AND token = 'Cz32q82v8MUjzSTRjK/5UBS2BmrfsHnB0yjsKwZ5f1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}