SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2478703f593294217563951d0217cd960500cd6b1598e68069950c55fc6b626' 
  AND token = 'JSvcxAfsJ3ypKQMm/ex5TtR8Ha5LtlYuuNvQonsIolY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}