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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4845dbe5e79ec0dd20341d015456f59742e6208537f61317b287d647496aa1' 
  AND token = 'beZq3aqQcxKi/Q4ykm2Hr07x3AuyiqJ2B2RSzjlvcxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}