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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2679705eb6a15235336d7e9d9aadc82e7691025314a50dd380e55020c579e1a' 
  AND token = 'KUWFHGDLO2pkp5dozqNaGlry6TUtS83nbXUXcKXjVBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}