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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b87922cb9e77b59da60cd51f3b0e7142163d268eaba6c6cc1f817e5241fc6cfd' 
  AND token = '+JZW1CjQWXxchZjVxEcmrDYCle10tYH5M5P9ZBoM2Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}