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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87da665bb8fc2592e56c0a5f0281a84808a55afff56ebf21ad888a38a8b69393' 
  AND token = 'FrWX0QwW21mnEbXMXXdLwqTQjlVxDE/SuSeo4G6KZEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}