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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acfe81e1e8791818a10ee42708e02dbc67feb8c1a02377224de1c94936bd503e' 
  AND token = 'I3XuDzxfPNjuCsuMo9vqN2g4BUUq9LE+zo3DLsRCgAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}