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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fed73675782f5bdd35c33bf0f4dec37e8e7c6151265ba4a942166232116e9225' 
  AND token = 'hd7zZuIDzNlXXnEx4IOPMtCbBw/ri52CWc4iMZi9ikc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}