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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed8d860e64ff30e8741c5a4518709982124af87fd7bb19c8df70b03686b96005' 
  AND token = 'GUuWCp2o44Z2Pnfo1FYd4P9xQ1srVgTP/1EAuIbC140=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}