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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53934207325a297eed8dd8447998cb2e89f5f186870288775522a131899296a' 
  AND token = 'u5SV1AQ1b2sXAVk9iLtpEeYoU1GRtpEIPUGBL9t7NFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}