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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c5208e51e9cad2ca3f41edc51a5cf64860c82b7484f0644aefacaca914bb81' 
  AND token = 'ed1LshN35povrH+hijKByFuQQ0xAMHD20NORZo0WEnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}