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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb9d87b0efbf3c309606cda9c66809d536fc0de23bf0829b4a2bf3ec46eb0a0' 
  AND token = 'Co4OSr/XOchzaYVFL1sxPyo7YkCgsS4sgNhhBdo/jpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}