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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c3ea466f646e2cac9ed4a1bc4c32802bf8b023b512a7452d9bf20dfe45a1d8' 
  AND token = 'tSsVJn03Xa9n1vdgbDHqKfl4K1DEYMAT1rITR7uuniU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}