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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d4afbc72cb56b74cab89b0f5538c4640294fdc30fbd1feb16b180153effc55f' 
  AND token = 'Zbg1/xEYRO4AgHga+dHvG46NaC4p29q2rlbSUtwwUbs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}