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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c506b2e929e1a3ccacef58993de780e0faffe4523adb89ee20dd3b336ed5c828' 
  AND token = 'yxXxGvbq2CwYhNKdjGfkFT0KPGkMbj43q4KZCW257Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}