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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df546714132700ae7e7fd0b4b5f5017b0e9756539d7d19a2146aff020ef15fed' 
  AND token = 'IusZO5p2TWeqSmGw66WM5LqYJoD2NPv7wK7Vmg3HxIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}