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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ecb0db9325179295a4139717166a3938d828fc2f8602f48b51c638859080e09' 
  AND token = 'gMI4TCu94QX71yN3faR3qaswq+tybhgpUPp1vcmbcBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}