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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e6f5c2727476c7ffec50e7876735016ca49f935a2c9a94c255f7fc7328bbee' 
  AND token = 'mRlJ9Ag4Fjcbg+X1eiLyCFPmXRhpLQHsyZ4cR7EZ0LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}