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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74e2636f521968ea84604aa8c5336c43b25ccbd85d9b0b9c617c906610c73dc8' 
  AND token = 'S2+FWH7EK45bICQ+NYejl0UqsiUp/5XHT9K+C4qGU8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}