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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f07a526e5eed78f78a0fae7e3e19eecece8099179f62301ca4b6fd783d4abd85' 
  AND token = 'waPqVxy0TMuA4KzMvQHyebh3LyVauQdkzMWWxTeEQo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00125

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}