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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24884af869758b4c6577345b2735ff0e3da8f78c963c4933de0eadcc2cfd4e71' 
  AND token = 'u4z5B4DMQZKAewCATB1CTlWEp/r/6SjgfRtIL0eUfoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}