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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '807a19c207d0d3600940988647e2766a74c73225541c3022cf28b018b3390f13' 
  AND token = 'rdcaMtyWWvZaVpM0wORa7+6P5TF9AI5/MVVUI7lGzKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}