SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09de09962b4e25b881f3c6babf1acbcd6a92a3dff1c8fcf098efec1ae27833f0' 
  AND token = 'PRX4H1++9c4KybHwUiLMDhoIY7WUW7mdyF+jqOk3I1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}