SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e334c1b3502486a2cc89f162718f0cfa95870d2ef7eb10994edb5aff25c3bbd2' 
  AND token = 'QZPUZ5v4RlwLmyvSsdDvcEFRBp2TJnDuOoZakO9br/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}