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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a214f108a731e282b3cd7f84b462a594c4ba547c8cfde1e21e60e58c7beb947' 
  AND token = '0E9YyFrOI6BWkGszWsG6GBaMDE+7k4KaRKZ7K3JauQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}