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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeacf36cb24c3bd07792893c395e71999b7a517cfa7b4656f75d13867ea5ef15' 
  AND token = '3Cy3h21pTsMrJE5lpA76cqC5u4Ge+RFSmfyvYJLuiW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}