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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f23fb8b17dddf3ddb4c9977d225c4dc2ade35818bd7bdddaef9129cddc18f8' 
  AND token = 'aAfM0qBJNU4ewIgb5w0vCr1AFBhqB9gOESJbqQP1CDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}