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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd170a26d2097887649d4237d6b4d532820334b2f1e7ca8a426462c1c4435d7b9' 
  AND token = 'a5kMujizVbenwMmDndz0jbW4VOlHgGTzqsjiDjHmpIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}