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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '744474af5dd013df03e413a279691e78ea6bb0469496f1f18e185f89644f854a' 
  AND token = '6XJrIHyDaFtQbS1W5FM4whb89BGmBRvJPKl0bOjwaxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}