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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5655e258478439f946af8ea46630ea83fcc10661647ec9e42e7f293be9585888' 
  AND token = 'amCldrGjYsG1zengP+w8AasdGqiPR++kq+fGgWBubd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}