SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e09cdf6c9621feadc149b7aa1c918654bc10aca34fe0988f5f55408d0d7b6c78' 
  AND token = 'C+QPwW9rs9aQz1QEGM1BR70cLgR80HeG4Ttl2JZxDt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}