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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a8952ad0bf93bd8c8cef5f9bc74bde9cb0e29823e2760f9a33b0b5bfc3de4c' 
  AND token = '2y4SV+b188U/ClsyleQ5D0G+gYEcjKYsKezLMshh2BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}