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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16bcc6cf84f2f23c26d1fc429c029a098d7b5f8322f8aeeb663056632e876aa1' 
  AND token = 'hurNIGiC8pW9nP9PvwjSe6D0VvVgxw3bZnXV+f0xHPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}