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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10ea3312f7b28e59671d9ea5654db849aeb86cea217862b0eb5a50c130ffa4fb' 
  AND token = 'w4dNMDN3kBhwNQ8Y4+asMeYtWAOaMgZhryRgyV3W6tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}