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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a72d8854c9c9c634b0a0f2ceeec06b10bd0fd61f33499c85101a45f6cf115f20' 
  AND token = 'fxOO5kbewUq43NT2xeW3IhGCqyZwLW+I7+EQXNTHMgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}