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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6573d045c66afeddecf9510bed139b9601e5784a91979ba1a1d649a22f59cd5' 
  AND token = 'IH2lKc+a/Y/EbK9uTVvvTp7UySQNR3rkYR4V2j3w/W0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}