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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e147d8aec01a08f922d3caa347b3638dedbc5520db27bb718a246da47db1cbee' 
  AND token = 'a6sDGnzFXJAL6jmf6YlUpn7zdWCD0bQ/C4gsoWUeW3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}