SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c695d7debc87f17acc1a02bffe99bbe087ec1edad04a0b779ff81b7145ebab4' 
  AND token = 'XDaqVRAO02Ny6VeNu1NEC/ZvHbDUhq+ZSEyvAdqfleU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}