SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5323c46167abec07c98b9856b889b74fe8a5ead61160c2f888d43052aee4b5f' 
  AND token = 'udG6nqC/TzEJ7w6DcnM1r/c8SuJYwf286c8DD2ZhMRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}