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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728f217663383edaadb68c98e4245314f711ac157cfd96c34b7eb5a3c2deb86f' 
  AND token = 'FrRW0I3oEG4767EJ9Q9b2kn/XB4cXXhI2lwXuZAcFG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}