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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0472eac17e0bffc776bebcc80d8c03a4f71cb7366195a6452809a826418825c2' 
  AND token = 'fIhXTjOSRbcE6g8YiQ0zvz4E2+2ZS87qYcbqyVMfFQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}