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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff0bcd73510491c42c4cd1463c7505915f6a4fcd4fff4d44adf67009b2496984' 
  AND token = 'iUAkG7NwD2VcKWC+Qlpo3hX6pxBdzKBAyj3ewZe3oVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}