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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f492e7e408764b6b8d1a9d04fdda5031acdd9a0dd6269f1db2665eca3f44f3e7' 
  AND token = '1jzB9mdUYYdxWSzUilzzkvUiJkCsfsee6xqdwJDIjzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}