SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9839e20ec64b3d6344fa25a361505c2724aea0b8783eeedc9b5536f56fd6347c' 
  AND token = 'f3K00PDxH9cdkltrI453jAXwBp/GK/Sv3LEjxH0aVhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}