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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39aad4ddb8eabc4b890f990e4911bea2a56388380496ff03c4e13c426d9bc7b7' 
  AND token = '6V22RqHq2QmmWzYz0jlTC9CIGL7zzztklkL1RinDhPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}