SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8922950febc0b5eca32935b808bc874e61623da00dfc9de0fa94fcdc67f0b630' 
  AND token = 'AsQOQxj1/QLVzGWylw51OZ8C+hqm4tYI+PY7LM9SzUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}