SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28745803191f57f9a7a13a94261df82fd12f04516224add3f950b38d4c2b9e6b' 
  AND token = 'eD5D9SOaO8kj5xgwkansh3Bm86Vq5bWCbu1kcdo+KQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}